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Simple one-click file shrinker.Methylenetetrahydrofolate reductase gene C677T and A1298C polymorphisms and risk of cerebral hemorrhage in Chinese stroke patients. Stroke is the third leading cause of death and the leading cause of adult disability. Abnormal cerebral folate metabolism has been implicated in the pathogenesis of stroke. Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C gene polymorphisms are associated with reduced enzyme activity. However, the association of these polymorphisms with cerebral hemorrhage (CH) risk remains controversial. We investigated the relationship between MTHFR polymorphisms and CH risk in a case-control study of 201 CH patients and 200 controls. The genotyping was performed using a polymerase chain reaction-based restriction fragment length polymorphism (PCR-RFLP). There was no significant difference in the frequency of the MTHFR C677T and A1298C polymorphisms between CH patients and controls. MTHFR genotype frequencies in CH patients were significantly different from controls in the dominant model (TT+CT vs. CC, OR=1.89, 95% CI=1.15-3.11, P=0.011). However, the association between MTHFR C677T and A1298C polymorphisms and CH risk was not statistically significant (TT vs. CC, OR=1.16, 95% CI=0.77-1.74, P=0.472; AA vs. CC, OR=0.70, 95% CI=0.42-1.18, P=0.180; CA vs. CC, OR=0.98, 95% CI=0.68-1.42, P=0.932; AA+CA vs. CC, OR=0.93, 95% CI=0.64-1.37, P=0.732; TT vs. AA+CA, OR=0.86, 95% CI=0.62-1.20, P=0.379). Our results do not support a major role of the MTHFR C677T and A1298C polymorphisms in CH risk.1. Field of the Invention The present invention relates to an electromagnetic pickup device. 2. Description of Related Art In a magnetic disk device, a magnetic head which What's New in the? 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